SALT LAKE CITY, UTAH, USA, July 17, 2017 /EINPresswire.com/ -- Intermountain Precision Genomics announces two publications from Intermountain Healthcare’s clinicians and researchers that demonstrate the successful application of genomics approaches to studying individual cancer cases. Lincoln Nadauld, M.D., Ph.D., and Derrick Haslem, M.D., are medical oncologists at the Southwest Cancer Center in St. George, Utah. In addition to treating patients, these physicians conduct research to advance cutting edge cancer care and precision medicine on a broad continuum. Their recent research has been published in two national peer-reviewed journals: Genome Medicine and Journal of Clinical Oncology-Precision Oncology, in collaboration with Intermountain Healthcare doctors and researchers from Stanford School of Medicine.
The first study, published in the Journal of Clinical Oncology-Precision Oncology, a research publication outlet from the American Society of Clinical Oncologists, “outlines the impressive clinical course and positive outcome of a patient with metastatic colon cancer treated with a precision oncology approach.” The second publication, from Genome Medicine, on which Nadauld is a co-author, “demonstrates that linked read sequencing is useful in characterizing oncogenic rearrangements in cancer metastasis.” Both studies were carried out in collaboration with Hanlee P. Ji, M.D., Senior Associate Director of the Stanford Genome Technology Center and Associate Professor at Stanford’s School of Medicine.
Linked read sequencing is a process that allows scientists and doctors to look at the molecular structure of tumor DNA in “longer reads of 50,000 base pairs, versus the typical 200-300, revealing the genomic complexity of patient tumors.” In reference to the Genome Medicine study, Nadauld points out, “In this patient, we were able to identify an amplification of a gene called FGFR2, which is critical because there are drugs that target that mutation.” Nadauld adds, “This case indicates there are broader applications for linked read technology, including diagnostic purposes and defining additional treatment options for patients along with new genes to target. With further study, pharmaceutical and biotech technologies can start to develop new drugs that target different molecular phenomena.”
Intermountain Precision Genomics is a service of Intermountain Healthcare. For more information about Intermountain Precision Genomics, please visit: precisioncancer.org, join the dialog on Facebook (Intermountain Precision Genomics) or follow @precisioncancer on Twitter.
========================Information: Shayne Ward (385) 368-0403 What: Wildland fire, Human-Caused, Under investigation for exact source Started: 07/15/2017 at 8:12pm Location: 1 mile Northeast of Alpine, UT Jurisdiction: USFS, Northern Region, Uinta National Forest Current Size: 397 acres Current Containment: 25% Approximate costs to date: $300,000 Structures Lost: 0 Estimated Containment date: 07/20/2017 Agencies Involved: Local, State, and Federal agencies Resources: Type 3 Incident Management Team (Robison)
Hand Crews
Engines Crews
Airplanes Helicopters Bulldozers
Other Personnel
3 6 0 3 0 20
Weather Conditions: Close to triple digit heat with single digit relative humidity. Gentle, terrain driven winds.
Resources Threatened: Evacuations have been lifted. All structures that were threatened are now safe to enter. All road closures have been lifted, as well.
Yesterday’s Activity: The fire started later in the evening so aircraft were unable to engage. Initial attack firefighters were extremely effective in identifying and protecting threatened structures. Crews worked throughout the night bolstering homes defensible space. At 3:00am on Sunday, 25 homes were evacuated as the flame burned actively overnight.
Today’s Objectives: The fire died down as the sun came up, allowing crews on the ground and in the sky to be aggressive in their strategy and tactics. The lower portions of the fire were quickly suppressed. As the day went on, crews were able to move up the flanks of the fire, preventing it from moving up and down the valley. The only remaining active portion of the fire is higher up on the slope where it is burning in a wilderness area. In a conscious effort to preserve the area and limit the exposure to firefighters in steep rugged country, fire managers are utilizing natural geographic barriers as fuel breaks.
Tomorrows Objectives: Ground crews will continue to mop up the fire perimeter. Large increases in containment percentages are expected. Aerial resources will remain on scene and continue to contribute in suppression actions.
Remarks: Smoke will still be visible for many days as firefighters continue to contain and control the fire. Please be aware that the fire is still active and personnel will be moving in and out of the area.
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CUSTOM CULINARY, INC. RECALLS CHICKEN AND BEEF PRODUCTS
DUE TO MISBRANDING AND UNDECLARED ALLERGENS
WASHINGTON, July 14, 2017 – Custom Culinary, Inc., an Oswego, Ill. establishment, is recalling approximately 9,444 pounds of chicken and beef base products due to misbranding and undeclared allergens, the U.S. Department of Agriculture’s Food Safety and Inspection Service (FSIS) announced today. The products’ labels incorrectly identified the products as chicken, but may contain beef. Additionally, the products contain soy, a known allergen, which is not declared on the product label.
The chicken and beef soup base items were packaged on May 25, 2017. The following products are subject to recall:
The products subject to recall bear establishment number “EST. 2016” or “EST. P-1278” inside the USDA mark of inspection. These items were shipped to food service distributors nationwide.
The problem was discovered when one of the company’s foodservice distributors was notified that a customer had received a case of product with mislabeled jars. The jar received was a beef base labeled as chicken base.
There have been no confirmed reports of adverse reactions due to consumption of these products. Anyone concerned about an injury or illness should contact a healthcare provider.
Consumers who have purchased these products are urged not to consume them. These products should be thrown away or returned to the place of purchase.
FSIS routinely conducts recall effectiveness checks to verify recalling firms notify theircustomers of the recall and that steps are taken to make certain that the product is no longer available to consumers. When available, the retail distribution list(s) will be posted on the FSIS website at www.fsis.usda.gov/recalls.
Consumers with questions about the recall can contact Scott Freitag, Vice President of Quality Systems & Regulatory, at (630) 299-0501. Media with questions about the recall can contact David Love, Vice President of Supply Chain & Operations, at (630) 299-0502.
Consumers with food safety questions can "Ask Karen," the FSIS virtual representative available 24 hours a day at AskKaren.gov or via smartphone at m.askkaren.gov. The toll-free USDA Meat and Poultry Hotline 1-888-MPHotline (1-888-674-6854) is available in English and Spanish and can be reached from 10 a.m. to 6 p.m. (Eastern Time) Monday through Friday. Recorded food safety messages are available 24 hours a day. The online Electronic Consumer Complaint Monitoring System can be accessed 24 hours a day at: http://www.fsis.usda.gov/reportproblem
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Shining a bright light on flaws in Duke University study of North Carolina’s Opportunity Scholarship Program
(WASHINGTON, DC) – A white paper produced by Parents for Educational Freedom in North Carolina (PEFNC) “is not only a victory for scholarship programs but for honesty in research,” according to Jeanne Allen, Founder and CEO of the Center for Education Reform.
The paper, developed by PEFNC’s Brian Jodice, catalogs an array of unbalanced comparisons, selective use of test performance data and unfair, unjustified conclusions that are among the many flaws in a recent Duke University study critical of the North Carolina Opportunity Scholarship Program.
“The data analysis strategy for the Duke report is poorly designed, using both different comparison groups and different tests,” Allen pointed out. “Moreover, scholarship students who tend to be predominantly from lower-income families are matched against a national sampling of students who come from a cross-section of socio-economic backgrounds, creating an apples-to-oranges comparison,” she added.
“The Duke study completely ignores the good news from the North Carolina program and other school choice programs around the nation,” Allen noted. “More than half of the 740 private schools in North Carolina participate in the program and more than 90 percent of first-year enrollees opt to enroll their children for a second year – arguably, the most important statistic of all.”
Read Allen's full statement here.
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DENVER—In the first offshore oil lease sale of the Trump administration, Interior Secretary Ryan Zinke decided to cut royalty rates from 18.75 percent to 12.5 percent. This is the rate paid by oil companies to taxpayers in return for drilling and selling publicly owned resources.
The decision comes on the heels of the Government Accountability Office raising red flags about already-low royalty rates for drilling on U.S. public lands. The Interior Department's management of oil and gas resources remains on the GAO’s high-risk list for fraud, waste, and abuse because it is not collecting a fair return from oil and gas development.
The Center for Western Priorities released the following statement from Deputy Director Greg Zimmerman:
“Lowering already-low royalty rates is deeply irresponsible. This is another signal that Secretary Zinke will happily hand out sweetheart deals to his friends in the oil business while ripping off American taxpayers.”
President George W. Bush and his Interior Secretary Dirk Kempthorne raised offshore royalty rates to 18.75 percent. The proposal to lower rates to match the onshore rate of 12.5 percent directly contradicts the Government Accountability Office, which has not only encouraged the Interior Department to increase royalty rates, but found that increases would generate new revenue and have a negligible impact on production.
Revenues generated from oil and gas production on U.S. public lands and waters is one of the federal government’s largest sources of non-tax revenue.
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The Center for Western Priorities is a conservation policy and advocacy organization focused on land and energy issues across the American West.
